SCHEMBL14286644

SCHEMBL14286644

O=C(Cc1c[nH]cn1)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 1/20 0.35
▸ ADORA2A P29274 1/20 0.35
▸ ADORA2B P29275 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.32
▸ MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3516117 0.87 ADORA3 (0.34) ADORA3ADORA2AADORA2B
Trifluoroacetic Acid SCHEMBL3514923 0.80 PSMB8 (0.32) ADORA3ADORA2AADORA2B
SCHEMBL5554652 0.74 — —
SCHEMBL21694902 0.74 DNMT1 (0.33) —
SCHEMBL45123 0.74 KDM4E (0.46) KDM4E
SCHEMBL8142065 0.73 RAB9A (0.43) KDM4E
Hydrochloric Acid SCHEMBL44961 0.72 KDM4E (0.44) KDM4E
SCHEMBL1441637 0.71 KMT2A (0.44) KDM4E
SCHEMBL27456186 0.71 KDM4E (0.32) KDM4E
SCHEMBL10029753 0.71 CAPN1 (0.39) ADORA3ADORA2AADORA2BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 — — US disclosed
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 — — US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 — — US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 ADORA3 2706/4885ADORA2A 1784/4885ADORA2B 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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