Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.52 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.48 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287238 | 0.91 | UCHL1 (0.51) | UCHL1DGAT2MGAT2ADORA1ABHD6 | |
| SCHEMBL14287233 | 0.90 | DGAT2 (0.50) | UCHL1DGAT2MGAT2ADORA1ABHD6 | |
| SCHEMBL14287224 | 0.86 | UCHL1 (0.52) | UCHL1DGAT2MGAT2ADORA1ABHD6 | |
| SCHEMBL16518191 | 0.83 | UCHL1 (0.62) | UCHL1DGAT2MGAT2ABHD6ESR2 | |
| SCHEMBL14287222 | 0.83 | MGAT2 (0.48) | UCHL1DGAT2MGAT2ADORA1ABHD6 | |
| SCHEMBL14287223 | 0.81 | DGAT2 (0.49) | UCHL1DGAT2MGAT2ADORA1ABHD6 | |
| SCHEMBL30200681 | 0.79 | P2RX3 (0.45) | ADORA1ESR2MAPK1PTGDR2P2RX3 | |
| SCHEMBL29801280 | 0.79 | ESR2 (0.54) | UCHL1ADORA1ABHD6ESR2MAPK1 | |
| SCHEMBL1570606 | 0.79 | ESR2 (0.54) | UCHL1ADORA1ABHD6ESR2MAPK1 | |
| SCHEMBL14287227 | 0.79 | DGAT2 (0.49) | UCHL1DGAT2MGAT2ADORA1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | UCHL1 3056/4885DGAT2 371/4885MGAT2 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.