Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288549 | 0.93 | NAAA (0.51) | MEN1KMT2ANPSR1HTTLMNA | |
| SCHEMBL14288548 | 0.93 | NAAA (0.51) | MEN1KMT2ANPSR1HTTLMNA | |
| SCHEMBL14303134 | 0.86 | ALDH1A1 (0.48) | MEN1KMT2ANPSR1TSHRHTT | |
| SCHEMBL14304765 | 0.83 | LMNA (0.45) | MEN1KMT2ANPSR1TSHRHTT | |
| SCHEMBL14304267 | 0.82 | SIGMAR1 (0.42) | NPSR1TSHRHTTLMNASMN1; SMN2 | |
| SCHEMBL11134932 | 0.81 | TSHR (0.47) | MEN1KMT2ANPSR1TSHRHTT | |
| SCHEMBL29173725 | 0.77 | L3MBTL1 (0.37) | MEN1KMT2ANPSR1TSHRLMNA | |
| Triphenylphosphine Oxide SCHEMBL27646660 | 0.77 | LMNA (0.59) | MEN1KMT2ANPSR1HTTLMNA | |
| SCHEMBL7405399 | 0.77 | NAAA (0.50) | MEN1KMT2ANPSR1HTTNAAA | |
| SCHEMBL8721542 | 0.77 | NAAA (0.50) | MEN1KMT2ANPSR1HTTNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |