SCHEMBL1428967

SCHEMBL1428967

N#Cc1ccc(OCCCBr)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.53
MAPT P10636 2/20 0.51
ALDH1A1 P00352 1/20 0.51
HRH2 P25021 6/20 0.50
HRH1 P35367 6/20 0.50
MMP2 P08253 3/20 0.50
MAOB P27338 1/20 0.48
MMP3 P08254 3/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
MMP13 P45452 1/20 0.46
TBXAS1 P24557 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7611407 0.98 HRH3 (0.51) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL15810293 0.94 MMP2 (0.58) HRH3HRH2HRH1MMP2MMP3
SCHEMBL1713933 0.94 ALDH1A1 (0.54) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL3107072 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL22401643 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL11031564 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL1999659 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL14448890 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL5522642 0.92 HRH3 (0.57) HRH3MAPTALDH1A1HRH2HRH1
SCHEMBL1018896 0.89 ALDH1A1 (0.53) HRH3MAPTALDH1A1HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388581-A1 ORGANIC COMPOUNDS INTRA CELLULAR THERAPIES INC (US) 2025-12-25 US disclosed
US-20250312340-A1 METHODS OF TREATING NEUROPATHIC PAIN INTRA-CELLULAR THERAPIES, INC. 2025-10-09 US disclosed
US-12331052-B2 Organic compounds INTRA-CELLULAR THERAPIES, INC. (US) 2025-06-17 US disclosed
US-20240415832-A1 NOVEL METHODS INTRA-CELLULAR THERAPIES, INC. 2024-12-19 US disclosed
EP-4419523-A1 NOVEL METHODS Intra-Cellular Therapies, Inc. (US) 2024-08-28 EP disclosed
CN-118556058-A New method 细胞内治疗公司 2024-08-27 CN disclosed
CN-118105390-A Method for treating addiction 细胞内治疗公司 2024-05-31 CN disclosed
WO-2023069880-A1 NOVEL METHODS INTRA-CELLULAR THERAPIES, INC. (US) 2023-04-27 WO disclosed
US-20220184072-A1 METHODS OF TREATING NEUROPATHIC PAIN INTRA-CELLULAR THERAPIES, INC. 2022-06-16 US disclosed
US-20220088014-A1 METHODS OF TREATING ADDICTION INTRA-CELLULAR THERAPIES, INC. 2022-03-24 US disclosed
US-5877174-A ANTICOAGULANTS TOYAMA CHEMICAL CO., LTD. (JP) 1999-03-02 US disclosed
EP-0485965-B1 Photographic silver halide material and process EASTMAN KODAK CO (US) 1998-10-14 EP disclosed
EP-0805149-A1 NOVEL 2,3-DIKETOPIPERAZINE DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 1997-11-05 EP disclosed
EP-0403019-B1 Photographic material and process EASTMAN KODAK CO (US) 1995-09-13 EP disclosed
US-5135839-A Coupler mixture EASTMAN KODAK COMPANY (US) 1992-08-04 US disclosed
EP-0485965-A1 Photographic silver halide material and process EASTMAN KODAK COMPANY (US) 1992-05-20 EP disclosed
US-5006448-A Containing compound capable of releasing development inhibitor EASTMAN KODAK COMPANY (US) 1991-04-09 US disclosed
EP-0403019-A2 Photographic material and process EASTMAN KODAK COMPANY (US) 1990-12-19 EP disclosed
EP-0111345-A2 Isoxazoles, useful as antiviral agents, and preparation thereof STERLING DRUG INC. (US) 1984-06-20 EP disclosed
US-4451476-A Isoxazoles as antiviral agents STERLING DRUG INC. (US) 1984-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312340-A1 METHODS OF TREATING NEUROPATHIC PAIN GAP43, OPRK1, CNR2 HRH3 276/4885MAPT 1091/4885ALDH1A1 1202/4885
US-20250388581-A1 ORGANIC COMPOUNDS OPRD1, OPRM1, HTR2C HRH3 238/4885MAPT 1426/4885ALDH1A1 943/4885
US-12331052-B2 Organic compounds OPRD1, OPRK1, OPRM1 HRH3 386/4885MAPT 1448/4885ALDH1A1 942/4885
US-20240415832-A1 NOVEL METHODS OPRK1, OPRD1, OPRM1 HRH3 249/4885MAPT 4104/4885ALDH1A1 872/4885
US-20220088014-A1 METHODS OF TREATING ADDICTION OPRK1, OPRM1, OPRD1 HRH3 254/4885MAPT 1740/4885ALDH1A1 322/4885
US-20220184072-A1 METHODS OF TREATING NEUROPATHIC PAIN GAP43, OPRK1, CNR2 HRH3 276/4885MAPT 1091/4885ALDH1A1 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.