Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CASP14 | P31944 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293956 | 0.94 | RAB9A (0.53) | RAB9ARPS6KA6CTSLCTSBCTSS | |
| SCHEMBL14293983 | 0.87 | RAB9A (0.53) | RAB9ACTSLCTSBCTSSCTSK | |
| SCHEMBL4839000 | 0.86 | CTSL (0.56) | IDH2CTSLCTSBCTSSCTSK | |
| SCHEMBL14300476 | 0.85 | TNIK (0.43) | RAB9ARPS6KA6TNK2SYK | |
| SCHEMBL14294391 | 0.81 | RAB9A (0.62) | RAB9ACTSLCTSBCTSSCTSK | |
| SCHEMBL4837042 | 0.81 | IDH2 (0.55) | RAB9ARPS6KA6IDH2CTSLCTSB | |
| SCHEMBL14294112 | 0.81 | RAB9A (0.45) | RAB9ARPS6KA6CTSLCTSBCTSS | |
| SCHEMBL14294400 | 0.81 | ROCK1 (0.52) | RAB9ACTSLCTSBCTSSCTSK | |
| SCHEMBL14294421 | 0.81 | RAB9A (0.46) | RAB9ARPS6KA6TNK2CTSLCTSB | |
| SCHEMBL4829395 | 0.81 | CTSS (0.53) | RAB9AIDH2CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332490-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332488-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |