Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CASP14 | P31944 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TXN | P10599 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294391 | 0.94 | RAB9A (0.62) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL14294396 | 0.88 | APP (0.56) | APPCA12CA1CA2CA9 | |
| SCHEMBL14293828 | 0.87 | RAB9A (0.44) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL4839000 | 0.86 | CTSL (0.56) | APPCTSLCTSSCTSKCTSB | |
| SCHEMBL14300020 | 0.85 | TXN (0.54) | APPCA12CA1CA2CA9 | |
| SCHEMBL14302762 | 0.85 | RAB9A (0.53) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL14293956 | 0.81 | RAB9A (0.53) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL4832399 | 0.81 | RAB9A (0.53) | RAB9AAPP | |
| SCHEMBL4832885 | 0.81 | RAB9A (0.65) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL14294421 | 0.81 | RAB9A (0.46) | RAB9ACTSLCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332490-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332488-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |