Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | TXN | P10599 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14300020 | 0.97 | TXN (0.54) | APPCA12CA1CA2CA9 | |
| SCHEMBL14293983 | 0.88 | RAB9A (0.53) | APPCA12CA1CA2CA9 | |
| SCHEMBL14294391 | 0.84 | RAB9A (0.62) | — | |
| SCHEMBL14302322 | 0.82 | GALR1 (0.47) | APPCA12CA1CA2CA9 | |
| SCHEMBL14300476 | 0.80 | TNIK (0.43) | APPMAPTTNIK | |
| SCHEMBL4838360 | 0.79 | NFKB1 (0.52) | APPCA12CA1CA2CA9 | |
| SCHEMBL5033983 | 0.77 | APP (0.60) | APPCA12CA1CA2CA9 | |
| SCHEMBL14268288 | 0.77 | NFKB1 (0.57) | APPCA12CA1CA2CA9 | |
| SCHEMBL4836537 | 0.76 | APP (0.63) | APPCA12CA1CA2CA9 | |
| SCHEMBL1392126 | 0.76 | APP (0.77) | APPCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332490-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |