Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18589370 | 1.00 | NPC1 (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL1429462 | 1.00 | NPC1 (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL10132321 | 0.88 | LMNA (0.60) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL14037470 | 0.87 | NPC1 (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL10132243 | 0.87 | NPC1 (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL20482057 | 0.87 | NPC1 (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL3530509 | 0.87 | NPC1 (0.57) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL5408443 | 0.87 | NPC1 (0.57) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL10132411 | 0.86 | LMNA (0.58) | NPC1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL10132502 | 0.86 | NPC1 (0.55) | NPC1ALDH1A1MEN1KMT2AUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190345137-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2019-11-14 | — | — | US | disclosed |
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2019-02-19 | — | — | US | disclosed |
| EP-2300454-B1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-21 | — | — | EP | disclosed |
| US-8623902-B2 | Microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20110207781-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2300454-A1 | Novel Microbiocides | Syngenta Participations AG (CH) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009153191-A1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345137-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | CHIA, CHIT1, AADAC | NPC1 2044/4885ALDH1A1 1830/4885MEN1 1726/4885 |
| US-20110207781-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | NPC1 460/4885ALDH1A1 433/4885MEN1 3185/4885 |
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | CHIA, CHIT1, AADAC | NPC1 2044/4885ALDH1A1 1830/4885MEN1 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.