Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12345126 | 0.88 | RAB9A (0.34) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL27756872 | 0.82 | RORC (0.40) | GAAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL13108619 | 0.82 | RORC (0.40) | GAAKDM4EMAPTALDH1A1CYP3A4 | |
| SCHEMBL12345111 | 0.77 | RAB9A (0.33) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345095 | 0.76 | CTSK (0.35) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345119 | 0.76 | RAB9A (0.33) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345046 | 0.76 | RAB9A (0.36) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345092 | 0.76 | RAB9A (0.36) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345114 | 0.75 | STAT3 (0.32) | GAAKDM4EMAPTNPSR1MAPK1 | |
| SCHEMBL12345089 | 0.74 | STAT3 (0.33) | L3MBTL1GAAKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |