Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.59 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611760 | 0.86 | FAAH (0.63) | FAAH | |
| SCHEMBL19066596 | 0.86 | FAAH (0.63) | FAAH | |
| SCHEMBL610620 | 0.83 | PRMT6 (0.57) | ACHEHRH3FAAHKDM4EPOLB | |
| SCHEMBL30889265 | 0.83 | PRMT6 (0.57) | ACHEHRH3FAAHKDM4EPOLB | |
| SCHEMBL23916559 | 0.82 | MC4R (0.57) | HTR7HRH3FAAH | |
| SCHEMBL609148 | 0.81 | SMN1; SMN2 (0.58) | ACHEHRH3FAAHKDM4EPOLB | |
| SCHEMBL817090 | 0.81 | SMN1; SMN2 (0.58) | ACHEHRH3FAAHKDM4EPOLB | |
| SCHEMBL14305457 | 0.81 | HRH3 (0.67) | ACHEHTR7HRH3BACE1PARP1 | |
| SCHEMBL2462639 | 0.80 | ACHE (0.65) | ACHEHTR7HRH3KDM4EPOLB | |
| SCHEMBL19066585 | 0.80 | FAAH (0.57) | FAAHKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891954-A2 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2008-02-27 | — | — | EP | disclosed |