Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145260 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL12062913 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL8146212 | 0.85 | GAA (0.63) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL12508636 | 0.84 | CYP4F2 (0.51) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL14354579 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL2094025 | 0.84 | GAA (0.53) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL8147121 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL8151837 | 0.84 | ALDH1A1 (0.66) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL15861906 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL8147823 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAGFERCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319155-B2 | 7,7-disubstituted (5H,9H)-6,8-dioxabenzocycloheptene compounds useful in the synthesis of non-steroidal analogues of vitamin D | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-01-15 | — | — | US | disclosed |
| EP-1341035-B1 | Silver halide color photographic light-sensitive material | FUJIFILM CORP (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117989-A1 | Methanesulfonic acid [7-(4-nitrophenyl)-(5H,9H)-6,8-dioxabenzocyclohepten-2-yl]methyl ester; chemical intermediates | CYP24A1, CYP2R1, VDR | ALDH1A1 1062/4885GAA 4214/4885GFER 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.