Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13252492 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL15846350 | 0.82 | TAS1R3 (0.43) | TAS1R3TAS1R1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL25841276 | 0.82 | SMN1; SMN2 (0.39) | TAS1R3TAS1R1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL23222118 | 0.79 | LMNA (0.44) | SMN1; SMN2KDM4ELMNATSHRHTT | |
| SCHEMBL26419315 | 0.78 | SMN1; SMN2 (0.41) | TAS1R3TAS1R1SMN1; SMN2LMNATSHR | |
| SCHEMBL3766820 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL23222128 | 0.75 | L3MBTL1 (0.45) | SMN1; SMN2LMNATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL26185780 | 0.74 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1KMT2ATHRA | |
| SCHEMBL19304479 | 0.73 | ALDH1A1 (0.43) | TAS1R3TAS1R1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9715780 | 0.72 | TAS1R3 (0.43) | TAS1R3TAS1R1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993831-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECH INC (US) | 2008-01-09 | — | — | EP | disclosed |