Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23222128 | 0.83 | L3MBTL1 (0.45) | SMN1; SMN2LMNAHDAC1HDAC2L3MBTL1 | |
| SCHEMBL26428761 | 0.81 | NAAA (0.65) | HDAC3L3MBTL1NAAAEPHX1ALDH1A1 | |
| SCHEMBL13509604 | 0.79 | L3MBTL1 (0.71) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL10099595 | 0.78 | L3MBTL1 (0.73) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL10595825 | 0.78 | L3MBTL1 (0.73) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL10994444 | 0.78 | L3MBTL1 (0.73) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL5694370 | 0.78 | L3MBTL1 (0.73) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL23222118 | 0.77 | LMNA (0.44) | SMN1; SMN2LMNAHDAC1HDAC2L3MBTL1 | |
| SCHEMBL15086079 | 0.76 | HTT (0.46) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13603740 | 0.76 | HDAC3 (0.55) | SMN1; SMN2LMNAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558384-B1 | MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-25 | — | — | EP | disclosed |
| US-7704912-B2 | Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-20060014981-A1 | Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014981-A1 | Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis | MDM4, HMBS, ICMT | SMN1; SMN2 4731/4885LMNA 4315/4885HDAC3 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.