SCHEMBL14306604

SCHEMBL14306604

CCN(C(=O)Oc1ccc(F)c(C)c1)[C@@H](C)c1ccc(O)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.39
ACHE P22303 3/20 0.39
FAAH O00519 1/20 0.39
MARK4 Q96L34 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PPARD Q03181 1/20 0.34
MAPK14 Q16539 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4779389 0.87 PPARG (0.37) BCHEACHEFAAHPPARGPPARA
SCHEMBL4908590 0.87 PPARG (0.37) BCHEACHEFAAHPPARGPPARA
SCHEMBL13899483 0.80 MEN1 (0.47) BCHEFAAHMEN1KMT2APPARG
SCHEMBL14281860 0.78 PPARG (0.36) BCHEACHEFAAHMEN1KMT2A
SCHEMBL10184452 0.76 BCHE (0.50) BCHEACHEFAAHMARK4MEN1
SCHEMBL4781589 0.73 PPARG (0.36) PPARGPPARA
SCHEMBL4904400 0.73 PPARG (0.36) PPARGPPARA
SCHEMBL19541466 0.71 RAB9A (0.60) BCHEACHEMEN1KMT2ANPSR1
SCHEMBL13721907 0.70 ALOX15 (0.42) MEN1KMT2APPARGPPARALMNA
SCHEMBL13721776 0.70 ALOX15 (0.42) MEN1KMT2APPARGPPARALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080009534-A1 SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD BRISTOL-MYERS SQUIBB COMPANY 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009534-A1 SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD GPR119, LIPC, CEL BCHE 1458/4885ACHE 3926/4885FAAH 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.