Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324750 | 0.82 | KDM4E (0.43) | L3MBTL1KDM4EPOLBCHEK1RAD52 | |
| SCHEMBL14197601 | 0.81 | RRM2 (0.48) | KDM4ENPC1KMT2A | |
| SCHEMBL18386498 | 0.78 | KCNH3 (0.48) | — | |
| SCHEMBL21388439 | 0.77 | MAPT (0.61) | L3MBTL1KDM4EPOLBALOX15RAD52 | |
| SCHEMBL12697198 | 0.77 | RRM2 (0.46) | KDM4E | |
| SCHEMBL23405971 | 0.76 | L3MBTL1 (0.50) | L3MBTL1KDM4EPOLBALOX15RAD52 | |
| SCHEMBL29744105 | 0.76 | L3MBTL1 (0.50) | L3MBTL1KDM4EPOLBALOX15RAD52 | |
| SCHEMBL25650053 | 0.75 | STK17A (0.42) | CHEK1 | |
| SCHEMBL9347587 | 0.75 | NPSR1 (0.40) | KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL20037762 | 0.75 | MAPT (0.43) | KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007123-A2 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |