Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372232 | 0.86 | ALDH1A1 (0.44) | CYP1A2ALDH1A1NAMPTL3MBTL1MAPT | |
| SCHEMBL22372092 | 0.78 | PHLPP2 (0.45) | CYP1A2ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL22372059 | 0.74 | GABRG2 (0.41) | CYP1A2ALDH1A1GABRPGABRDLMNA | |
| SCHEMBL1665229 | 0.74 | DAO (0.58) | CYP1A2KMT2AALDH1A1PDE4DNPSR1 | |
| SCHEMBL22372065 | 0.74 | CA12 (0.39) | CYP1A2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1019601 | 0.74 | CYP1A2 (0.59) | CYP1A2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1007015 | 0.73 | MAPK1 (0.61) | CYP1A2KMT2AALDH1A1MEN1PDE4D | |
| SCHEMBL163302 | 0.73 | KMT2A (0.54) | CYP1A2KMT2AALDH1A1PDE4DNPSR1 | |
| SCHEMBL1423671 | 0.73 | KMT2A (0.54) | CYP1A2KMT2APDE4DNPSR1L3MBTL1 | |
| SCHEMBL12827154 | 0.73 | THRB (0.52) | CYP1A2KMT2APDE4DNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116912-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260116911-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12264138-B2 | Process for the preparation of microbiocidal oxadiazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-01 | — | — | US | disclosed |
| EP-4472968-A1 | INHIBITORS OF RAF KINASES | PIERRE FABRE MEDICAMENT (FR) | 2024-12-11 | — | — | EP | disclosed |
| CN-118974036-A | Inhibitors of RAF kinase | 皮埃尔法布雷医药公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-112638376-B | Substituted tetrahydrocyclopenta [ c ] pyrroles, substituted dihydropyrrolidines, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2024-08-02 | — | — | CN | disclosed |
| US-20240182467-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2024-06-06 | — | — | US | disclosed |
| US-20240076310-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2024-03-07 | — | — | US | disclosed |
| US-20240025942-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240025942-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-8658635-B2 | Benzpyrazol derivatives as inhibitors of PI3 kinases | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2014-02-25 | — | — | US | disclosed |
| EP-2300437-B1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LTD (GB) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012158413-A2 | PYRROLIDINYL UREA AND PYRROLIDINYL THIOUREA COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | disclosed |
| US-20110178063-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178063-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178063-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| EP-2300437-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | Glaxo Group Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| WO-2009147188-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147188-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178063-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | PIK3CA, PIK3CD, PI4KA | CYP1A2 1867/4885KMT2A 3601/4885ALDH1A1 1833/4885 |
| US-20240076310-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | CNR1, NR3C2, CNR2 | CYP1A2 244/4885KMT2A 2650/4885ALDH1A1 604/4885 |
| US-20240182467-A1 | INHIBITORS OF RAF KINASES | BRAF, RAF1, ARAF | CYP1A2 4302/4885KMT2A 1631/4885ALDH1A1 2750/4885 |
| US-12264138-B2 | Process for the preparation of microbiocidal oxadiazole derivatives | CYP51A1, MPO, NOX5 | CYP1A2 30/4885KMT2A 4305/4885ALDH1A1 258/4885 |
| US-20260116912-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SCN4A, CHRNA4, CACNG4 | CYP1A2 857/4885KMT2A 3801/4885ALDH1A1 1606/4885 |
| US-20260116911-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SCN4A, CACNG4, SLC6A4 | CYP1A2 721/4885KMT2A 4007/4885ALDH1A1 1610/4885 |
| US-20240025942-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | GABRR1, NR3C2, GABRA1 | CYP1A2 288/4885KMT2A 1859/4885ALDH1A1 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.