Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.45 |
| ▸ | CLPP | Q16740 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | TCF7 | P36402 | 2/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14309405 | 0.97 | CYP3A4 (0.49) | MEN1KMT2ACYP3A4CLPPCTNNB1 | |
| SCHEMBL14504286 | 0.97 | CYP3A4 (0.49) | MEN1KMT2ACYP3A4CLPPCTNNB1 | |
| SCHEMBL14309434 | 0.94 | CLPP (0.48) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL14310092 | 0.92 | CLPP (0.57) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL14319181 | 0.92 | CLPP (0.57) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL14309879 | 0.91 | CTNNB1 (0.51) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL14319443 | 0.91 | CLPP (0.45) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL14309421 | 0.91 | CLPP (0.45) | MEN1KMT2ACYP3A4CLPPCTNNB1 | |
| SCHEMBL14504798 | 0.90 | HCRTR1 (0.42) | CYP3A4CLPPCTNNB1TCF7BCL9 | |
| SCHEMBL13773717 | 0.90 | CLPP (0.54) | CYP3A4CLPPCTNNB1TCF7BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957516-B1 | ALFA-HELIX MIMETICS AND METHOD RELATING TO THE TREATMENT OF CANCER STEM CELLS | CHOONGWAE PHARMA CORP (KR) | 2016-03-09 | — | — | EP | disclosed |
| US-20080009500-A1 | Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders | INSTITUTE FOR CHEMICAL GENOMICS | 2008-01-10 | — | — | US | disclosed |
| US-20070129353-A1 | Alpha-helix mimetics and method relating to the treatment of cancer stem cells | INSTITUTE FOR CHEMICAL GENOMICS | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009500-A1 | Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders | COL1A1, COL2A1, PLOD3 | MEN1 2759/4885KMT2A 4181/4885CYP3A4 4854/4885 |
| US-20070129353-A1 | Alpha-helix mimetics and method relating to the treatment of cancer stem cells | MCL1, HNF4A, THPO | MEN1 845/4885KMT2A 1448/4885CYP3A4 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.