Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432571 | 0.92 | LCK (0.41) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1432532 | 0.92 | MEN1 (0.48) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1431814 | 0.92 | MEN1 (0.48) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1432803 | 0.91 | CTSB (0.41) | MASP2MEN1KMT2APPIBITGA4 | |
| SCHEMBL1433004 | 0.91 | PPIB (0.43) | MASP2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1433193 | 0.90 | MEN1 (0.47) | MASP2MEN1KMT2APPIBITGA4 | |
| SCHEMBL1431881 | 0.90 | MASP2 (0.41) | MASP2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1432347 | 0.90 | MEN1 (0.47) | MASP2MEN1KMT2APPIBITGA4 | |
| SCHEMBL1432452 | 0.89 | TLR2 (0.42) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1432690 | 0.89 | TLR2 (0.42) | MASP2MEN1KMT2APPIBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |