Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27759241 | 1.00 | — | — | |
| Water SCHEMBL27856680 | 1.00 | — | — | |
| Water SCHEMBL28336806 | 1.00 | — | — | |
| Methane SCHEMBL27883739 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL27877104 | 0.87 | — | — | |
| Water SCHEMBL28887992 | 0.87 | — | — | |
| Water SCHEMBL2355031 | 0.82 | — | — | |
| Water SCHEMBL10747940 | 0.82 | — | — | |
| SCHEMBL168043 | 0.82 | — | — | |
| SCHEMBL21772634 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742085-B1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-12-01 | — | — | EP | disclosed |
| US-10358528-B2 | Viscoelastic silicone rubber compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180362717-A1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-12-20 | — | — | US | disclosed |
| US-10011686-B2 | Viscoelastic silicone rubber compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-07-03 | — | — | US | disclosed |
| US-20170233531-A1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-08-17 | — | — | US | disclosed |
| US-9550864-B2 | Viscoelastic silicon rubber compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2545103-B1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | Univ Virginia Patent Found (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20150344635-A9 | VISCOELASTIC SILICON RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2015-12-03 | — | — | US | disclosed |
| US-9102799-B2 | Viscoelastic silicone rubber compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150045471-A1 | VISCOELASTIC SILICON RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2015-02-12 | — | — | US | disclosed |
| US-20140364523-A1 | Viscoelastic Silicone Rubber Compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2014-12-11 | — | — | US | disclosed |
| US-8785507-B2 | Viscoelastic silicon rubber compositions | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2014-07-22 | — | — | US | disclosed |
| EP-2742085-A1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | University Of Virginia Patent Foundation (US) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013023174-A1 | VISCOELASTIC SILICONE RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2013-02-14 | — | — | WO | disclosed |
| US-20120329896-A1 | VISCOELASTIC SILICON RUBBER COMPOSITIONS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2012-12-27 | — | — | US | disclosed |