Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432148 | 0.92 | KMT2A (0.43) | PPIBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1432824 | 0.91 | MASP2 (0.41) | PPIBMEN1KMT2AKLKB1PKM | |
| SCHEMBL1432532 | 0.90 | MEN1 (0.48) | PPIBMEN1KMT2AALDH1A1MASP2 | |
| SCHEMBL1431814 | 0.90 | MEN1 (0.48) | PPIBMEN1KMT2AALDH1A1MASP2 | |
| SCHEMBL1432571 | 0.90 | LCK (0.41) | PPIBMEN1KMT2AMASP2 | |
| SCHEMBL1433193 | 0.87 | MEN1 (0.47) | PPIBTSHRMEN1KMT2AMASP2 | |
| SCHEMBL1432347 | 0.87 | MEN1 (0.47) | PPIBTSHRMEN1KMT2AMASP2 | |
| SCHEMBL1432690 | 0.86 | TLR2 (0.42) | PPIBMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL1432180 | 0.86 | DPP4 (0.40) | PPIBMEN1KMT2AALDH1A1KLKB1 | |
| SCHEMBL1432452 | 0.86 | TLR2 (0.42) | PPIBMEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |