Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433004 | 0.92 | PPIB (0.43) | KMT2AKLKB1PPIBFAPTSHR | |
| SCHEMBL1431672 | 0.92 | KMT2A (0.42) | KMT2AKLKB1PPIBTSHRLMNA | |
| SCHEMBL1432803 | 0.90 | CTSB (0.41) | KMT2AKLKB1PPIBALDH1A1MEN1 | |
| SCHEMBL1432409 | 0.90 | CTSL (0.48) | — | |
| SCHEMBL1432319 | 0.90 | KMT2A (0.43) | KMT2AKLKB1PPIBLMNAALDH1A1 | |
| SCHEMBL1433055 | 0.90 | KMT2A (0.43) | KMT2AKLKB1PPIBLMNAALDH1A1 | |
| SCHEMBL1432377 | 0.88 | MAPK14 (0.45) | KMT2ATSHR | |
| SCHEMBL1431638 | 0.87 | DPP4 (0.40) | KMT2AKLKB1PPIBLMNAALDH1A1 | |
| SCHEMBL1432180 | 0.87 | DPP4 (0.40) | KMT2AKLKB1PPIBLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1432515 | 0.86 | DPP4 (0.40) | KMT2AKLKB1PPIBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |