Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.41 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433349 | 0.87 | F2 (0.51) | MCHR1F2CTSLCTSSPYGL | |
| SCHEMBL1433255 | 0.86 | F2 (0.52) | MCHR1F2CTSLCTSSPYGL | |
| SCHEMBL1433514 | 0.84 | CCKBR (0.57) | CTSL | |
| SCHEMBL1433599 | 0.83 | PYGL (0.50) | F2PYGLMASP2HSPA8HSPA2 | |
| SCHEMBL1433165 | 0.82 | F2 (0.49) | MCHR1F2PYGL | |
| SCHEMBL1433554 | 0.82 | PYGL (0.52) | F2CTSLCTSSPYGLCTSK | |
| SCHEMBL1433533 | 0.79 | PYGL (0.49) | MCHR1F2CTSLCTSSPYGL | |
| SCHEMBL3157282 | 0.78 | F2 (0.49) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL1434686 | 0.77 | MCHR1 (0.55) | MCHR1F2CTSLCTSSPYGL | |
| SCHEMBL1432813 | 0.76 | HDAC3 (0.53) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |