SCHEMBL143348

SCHEMBL143348

Cc1cc(N(C)C)ccc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
CYP2A13 Q16696 1/20 0.48
MAPT P10636 2/20 0.47
ALDH1A1 P00352 6/20 0.45
TSHR P16473 3/20 0.45
KDM4E B2RXH2 2/20 0.45
GAA P10253 1/20 0.45
APAF1 O14727 1/20 0.43
TERT O14746 1/20 0.42
APP P05067 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
PKM P14618 1/20 0.41
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
ALOX15 P16050 2/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
PSMB5 P28074 1/20 0.39
IP6K1 Q92551 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5618881 0.85 ALDH1A1 (0.46) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL8964348 0.83 CYP2A6 (0.48) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL15982250 0.82 CYP2A6 (0.47) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL8488793 0.80 GRIN1 (0.40) MAPTALDH1A1TSHRKDM4EGAA
SCHEMBL2767322 0.80 ALDH1A1 (0.38) CYP2A6CYP2A13ALDH1A1TSHRKDM4E
SCHEMBL3669876 0.79 APAF1 (0.43) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL7671562 0.79 CYP2A6 (0.48) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL14940724 0.79 ALDH1A1 (0.41) CYP2A6CYP2A13MAPTALDH1A1TSHR
SCHEMBL2845181 0.79 ALDH1A1 (0.63) MAPTALDH1A1TSHRKDM4ETERT
SCHEMBL11142526 0.78 ALDH1A1 (0.43) CYP2A6CYP2A13MAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707994-A Tubulin inhibitor for overcoming taxol resistance, preparation method and medical application thereof 马鞍山十七冶医院 2025-03-28 CN claimed
CN-118955520-A Tubulin inhibitor for overcoming taxol resistance, preparation method and medical application thereof 马鞍山十七冶医院 2024-11-15 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP claimed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
WO-2021013420-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2021-01-28 WO claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed
JP-2000501697-A 2000-02-15 JP claimed
EP-0857067-A1 RADIOPROTECTORS The Inner and Eastern Health Care Network (AU) 1998-08-12 EP claimed
WO-1997004776-A1 RADIOPROTECTORS THE INNER AND EASTERN HEALTH CARE NETWORK (AU) 1997-02-13 WO claimed
US-4360660-A Triphenylmethane polymer, process for production thereof, and photoconductive compositions and members formed therefrom FUJI PHOTO FILM CO., LTD. (JP) 1982-11-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 CYP2A6 2524/4885CYP2A13 3216/4885MAPT 1677/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO CYP2A6 562/4885CYP2A13 379/4885MAPT 2879/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO CYP2A6 562/4885CYP2A13 379/4885MAPT 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.