SCHEMBL143375

SCHEMBL143375

NCC(O)Cn1ccnc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.51
AGER Q15109 1/20 0.51
FDPS P14324 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9022668 0.98 CYP19A1 (0.50) CYP19A1AGERFDPS
Water SCHEMBL9022662 0.98 CYP19A1 (0.50) CYP19A1AGERFDPS
SCHEMBL10247560 0.87 AGER (0.62) CYP19A1AGERFDPS
Hydrochloric Acid SCHEMBL1775858 0.85 AGER (0.60) CYP19A1AGERFDPS
SCHEMBL11292777 0.82 AGER (0.53) CYP19A1AGERFDPS
SCHEMBL1585079 0.82 AGER (0.53) CYP19A1AGERFDPS
SCHEMBL10730735 0.82 AGER (0.53) CYP19A1AGERFDPS
SCHEMBL6003232 0.80 FDPS (0.55) CYP19A1AGERFDPS
SCHEMBL412063 0.80 AGER (0.51) CYP19A1AGERFDPS
Hydrochloric Acid SCHEMBL11288977 0.80 AGER (0.51) CYP19A1AGERFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377651-B Cationic lipid with side chain containing functional groups and application thereof 厦门赛诺邦格生物科技股份有限公司 2025-04-01 CN disclosed
US-20250034080-A1 CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2025-01-30 US disclosed
EP-4458805-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2024-11-06 EP disclosed
CN-117377651-A Cationic lipid with side chain containing functional groups and application thereof 厦门赛诺邦格生物科技股份有限公司 2024-01-09 CN disclosed
WO-2023126006-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2023-07-06 WO disclosed
US-20150126679-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES HENKEL AG & CO KGAA (DE) 2015-05-07 US disclosed
US-20150126669-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES HENKEL AG & CO KGAA (DE) 2015-05-07 US disclosed
EP-2430073-B1 CATIONIC BENZOXAZINE (CO)POLYMERS HENKEL AG & CO KGAA (DE) 2015-01-07 EP disclosed
EP-2430137-B1 COLOR-PROTECTING WASHING OR CLEANING AGENT HENKEL AG & CO KGAA (DE) 2014-11-12 EP disclosed
US-8580726-B2 Color-protecting washing or cleaning agent HENKEL AG & CO. KGAA (DE) 2013-11-12 US disclosed
WO-2010018198-A1 POLYMERIZABLE BENZOXAZINE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2010-02-18 WO disclosed
CN-101400656-A Piperazine derivatives as farnesyl protein transferase inhibitors SCHERING CORP (US) 2009-04-01 CN disclosed
US-20070213340-A1 Farnesyl protein transferase inhibitors SCHERING CORPORATION 2007-09-13 US disclosed
US-20070213340-A1 Farnesyl protein transferase inhibitors SCHERING CORPORATION 2007-09-13 US disclosed
WO-2007084498-A1 PIPERAZINE DERIVATIVES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS SCHERING CORPORATION (US) 2007-07-26 WO disclosed
CN-1326850-C Tricyclic farnesyl protein transferase inhibitors SCHERING CORP (US) 2007-07-18 CN disclosed
CN-1334811-A Tricyclic farnesyl protein transferase inhibitors SCHERING CORP (US) 2002-02-06 CN disclosed
EP-0705251-A1 IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS Knoll AG (DE) 1996-04-10 EP disclosed
US-5081131-A Omega-((hetero)alkyl)benz(cd)-indol-2-amines AMERICAN CYANAMID COMPANY (US) 1992-01-14 US disclosed
EP-0230035-A2 Omega-[(hetero)alkyl]benz[cd]indol-2-amines AMERICAN CYANAMID COMPANY (US) 1987-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126679-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES CYP4Z1, PRDX4, PRDX1 CYP19A1 291/4885AGER 2366/4885FDPS 1566/4885
US-20070213340-A1 Farnesyl protein transferase inhibitors FNTB, FNTA, FDPS CYP19A1 1629/4885AGER 3807/4885FDPS 3/4885
US-20250034080-A1 CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF PHOSPHO1, LIPA, SLC7A1 CYP19A1 3836/4885AGER 3492/4885FDPS 4632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.