Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 8/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA4 | P22748 | 7/20 | 0.39 |
| ▸ | CA7 | P43166 | 7/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760054 | 0.84 | CA12 (0.57) | CA12CA2CA9CA1CA4 | |
| SCHEMBL7280720 | 0.72 | CA12 (0.54) | CA12CA2CA9CA1CA4 | |
| SCHEMBL392877 | 0.67 | POLB (0.36) | PDPK1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL13993207 | 0.67 | ADRA2C (0.38) | PDPK1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL49931 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL5624257 | 0.66 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGD | |
| SCHEMBL27591208 | 0.64 | PDPK1 (0.59) | CA12CA2CA9CA1PDPK1 | |
| SCHEMBL2768256 | 0.63 | HDAC3 (0.46) | CA12CA2CA9CA1PDPK1 | |
| SCHEMBL12054668 | 0.62 | KEAP1 (0.75) | CA12CA2CA9CA1ALDH1A1 | |
| SCHEMBL10360424 | 0.62 | HTR6 (0.66) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007150001-A1 | PYRRO[1,2-B]PYRIDAZINONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2007-12-27 | — | — | WO | disclosed |