SCHEMBL143382

SCHEMBL143382

COC1CCC2(CC1)NC(=O)C(c1cc(C)ccc1C)=C2O

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACACB O00763 13/20 0.70
ACACA Q13085 13/20 0.70
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
WEE1 P30291 1/20 0.35
THRB P10828 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143383 1.00 ACACB (0.70) ACACBACACACHRM2CHRM4CHRM5
SCHEMBL30057496 1.00 ACACB (0.70) ACACBACACACHRM2CHRM4CHRM5
SCHEMBL14700666 0.90 ACACB (0.66) ACACBACACA
SCHEMBL14689355 0.90 ACACB (0.66) ACACBACACA
SCHEMBL2347445 0.90 ACACB (0.66) ACACBACACA
SCHEMBL11989363 0.88 ACACB (0.56) ACACBACACACHRM2CHRM4CHRM5
SCHEMBL12778722 0.88 ACACB (0.56) ACACBACACACHRM2CHRM4CHRM5
SCHEMBL13527315 0.87 ACACB (0.62) ACACBACACAWEE1
SCHEMBL14704798 0.86 ACACB (0.56) ACACBACACAWEE1THRBCA1
SCHEMBL16490009 0.86 ACACB (0.56) ACACBACACAWEE1THRBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452446-B1 PROCESS FOR THE PREPARATION CIS-ALKOXYSUBSTITUTED SPIROCYCLIC 1-H-PYRROLIDIN-2,4-DIONE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2023-06-28 EP disclosed
US-20220132849-A1 USE OF SPIROPIDION SYNGENTA CROP PROTECTION AG (CH) 2022-05-05 US disclosed
EP-3372580-B1 METHOD FOR THE PREPARATION OF 1-H-PYRROLIDIN-2,4-DIONE-DERIVATIVES BAYER CROPSCIENCE AG (DE) 2020-07-22 EP disclosed
US-10577320-B2 Method for preparing cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-03-03 US disclosed
US-10435372-B2 Use of phenylpyrazolin-3-carboxylates for improving plant yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-10-08 US disclosed
EP-2964023-B1 USE OF N-(2-METHOXYBENZOYL)-4-[METHYLAMINOCARBONYL)AMINO]BENZENESULFONAMIDE IN COMBINATION WITH AN INSECTICIDE OR FUNGICIDE FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2019-08-07 EP disclosed
US-20190233369-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-08-01 US disclosed
US-10301257-B2 Use of acylsulfonamides for improving plant yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-05-28 US disclosed
US-20190144385-A1 Method for preparing cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-05-16 US disclosed
EP-2964027-B1 USE OF COMBINATIONS COMPRISING CLOQUINTOCET-MEXYL FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2019-04-24 EP disclosed
EP-1905300-A1 Water dispersible agrochemical formulations comprising polyalkoxytriglycerides as penetration promoters Bayer CropScience AG (DE) 2008-04-02 EP disclosed
EP-1891857-A1 Compositions for controlled release of agrochemicals Bayer CropScience AG (DE) 2008-02-27 EP disclosed
WO-2008006515-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed
WO-2008006514-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed
WO-2008006513-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed
WO-2008006516-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed
EP-1875804-A1 Liquid formulation containing pyrethroids Bayer CropScience AG (DE) 2008-01-09 EP disclosed
WO-2007140881-A1 ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS BAYER CROPSCIENCE AG (DE) 2007-12-13 WO disclosed
WO-2007031213-A1 DIOXAZINE- AND OXADIAZINE-SUBSTITUTED ARYLAMIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-22 WO disclosed
US-20070032539-A1 Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435372-B2 Use of phenylpyrazolin-3-carboxylates for improving plant yield CBR3, HRH4, HRH3 ACACB 1324/4885ACACA 720/4885CHRM2 314/4885
US-10577320-B2 Method for preparing cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives DHPS, DOHH, QDPR ACACB 1253/4885ACACA 1377/4885CHRM2 4220/4885
US-20190233369-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD ARSA, ACSS2, NAT1 ACACB 98/4885ACACA 69/4885CHRM2 1602/4885
US-20070032539-A1 Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides DDT, CYP4X1, PDHX ACACB 2047/4885ACACA 2002/4885CHRM2 168/4885
US-20190144385-A1 Method for preparing cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives DHPS, DOHH, QDPR ACACB 1253/4885ACACA 1377/4885CHRM2 4220/4885
US-10301257-B2 Use of acylsulfonamides for improving plant yield ARSA, ACSS2, NAT1 ACACB 98/4885ACACA 69/4885CHRM2 1602/4885
US-20220132849-A1 USE OF SPIROPIDION THOP1, SRD5A2, CYP21A2 ACACB 1272/4885ACACA 1268/4885CHRM2 784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.