Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14340926 | 0.85 | CYP2C19 (0.45) | EIF4A1CYP2C19RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3080086 | 0.82 | TSHR (0.49) | CYP2C19ALDH1A1TDP1CYP1A2HPGD | |
| SCHEMBL14340927 | 0.79 | EIF4A1 (0.46) | EIF4A1CYP2C19RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8974165 | 0.78 | NPC1 (0.53) | CYP2C19RAB9ANPC1MAPTLMNA | |
| SCHEMBL27617094 | 0.76 | RAB9A (0.56) | CYP2C19RAB9ANPC1MAPTLMNA | |
| SCHEMBL2947694 | 0.76 | TDP1 (0.61) | EIF4A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL14340928 | 0.76 | RAB9A (0.43) | EIF4A1CYP2C19RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14988202 | 0.74 | EIF4A1 (0.62) | EIF4A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28596462 | 0.73 | ALDH1A1 (0.57) | CYP2C19RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL22164075 | 0.73 | ELANE (0.48) | CYP2C19RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2007-12-06 | — | — | US | disclosed |
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | GPR119, FFAR1, HCAR1 | EIF4A1 4722/4885CYP2C19 484/4885RAB9A 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.