SCHEMBL143452

SCHEMBL143452

CCC([C]=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
MIF P14174 1/20 0.42
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HKDC1 Q2TB90 1/20 0.37
TRPA1 O75762 1/20 0.37
TAAR1 Q96RJ0 2/20 0.37
HTR2A P28223 2/20 0.37
HRH1 P35367 2/20 0.37
AOC3 Q16853 1/20 0.36
NOS3 P29474 1/20 0.36
NOS2 P35228 1/20 0.36
FFAR1 O14842 1/20 0.36
CCR5 P51681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8712988 1.00 LMNA (0.46) LMNAMIFPOLBMEN1KMT2A
SCHEMBL11258661 0.88 FFAR1 (0.50) SMN1; SMN2FFAR1
SCHEMBL142722 0.83 AOC3 (0.42) LMNAMIFPOLBSMN1; SMN2TAAR1
SCHEMBL28799952 0.83 AOC3 (0.42) LMNAMIFPOLBSMN1; SMN2TAAR1
SCHEMBL9725435 0.82 TRPA1 (0.40) LMNAMIFPOLBMEN1KMT2A
SCHEMBL10590199 0.80 CYP3A4 (0.40) LMNAPOLBHTTSMN1; SMN2
SCHEMBL143657 0.79 POLB (0.45) POLBHTR2AHRH1
SCHEMBL11211687 0.78 ALDH1A1 (0.41) LMNAMIFTRPA1TAAR1HRH1
SCHEMBL6447269 0.78 ESR1 (0.54) LMNAMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL7132895 0.78 GAA (0.36) LMNAPOLBMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063666-B Multifunctional polyester material and preparation method and application thereof 四川大学 2024-04-19 CN claimed
CN-116063666-A Multifunctional polyester material and preparation method and application thereof 四川大学 2023-05-05 CN claimed
US-20220401275-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2022-12-22 US claimed
CN-113444005-A Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin 四川大学 2021-09-28 CN claimed
CN-112043724-A Application of arsenic-containing compound 常州高新技术产业开发区三维工业技术研究所有限公司 2020-12-08 CN claimed
EP-3509647-B1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2020-10-21 EP claimed
EP-3509647-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS The Procter and Gamble Company (US) 2019-07-17 EP claimed
CN-109734619-A A method of impurity A, C are isolated and purified from phenobarbital production waste residue 山东新华制药股份有限公司 2019-05-10 CN claimed
EP-3294347-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2018-03-21 EP claimed
WO-2018048852-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS THE PROCTER & GAMBLE COMPANY (US) 2018-03-15 WO claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
US-4829053-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-05-09 US claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
US-4721776-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed