Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143452 | 1.00 | LMNA (0.46) | LMNAMIFPOLBMEN1KMT2A | |
| SCHEMBL11258661 | 0.88 | FFAR1 (0.50) | SMN1; SMN2FFAR1 | |
| SCHEMBL142722 | 0.83 | AOC3 (0.42) | LMNAMIFPOLBSMN1; SMN2TAAR1 | |
| SCHEMBL28799952 | 0.83 | AOC3 (0.42) | LMNAMIFPOLBSMN1; SMN2TAAR1 | |
| SCHEMBL9725435 | 0.82 | TRPA1 (0.40) | LMNAMIFPOLBMEN1KMT2A | |
| SCHEMBL10590199 | 0.80 | CYP3A4 (0.40) | LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL143657 | 0.79 | POLB (0.45) | POLBHTR2AHRH1 | |
| SCHEMBL11211687 | 0.78 | ALDH1A1 (0.41) | LMNAMIFTRPA1TAAR1HRH1 | |
| SCHEMBL6447269 | 0.78 | ESR1 (0.54) | LMNAMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL7132895 | 0.78 | GAA (0.36) | LMNAPOLBMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| EP-0837071-A1 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| CN-1036399-C | Tripeptide antithrombotic agents | LILLY CO ELI (US) | 1997-11-12 | — | — | CN | disclosed |
| EP-0685489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0684258-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5430023-A | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| CN-1060472-A | TRIPEPTIDE ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1992-04-22 | — | — | CN | disclosed |