Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211687 | 0.82 | ALDH1A1 (0.41) | TRPA1LMNAMIFTAAR1 | |
| SCHEMBL8712988 | 0.82 | LMNA (0.46) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL143452 | 0.82 | LMNA (0.46) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL5085704 | 0.76 | HRH1 (0.48) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL28799952 | 0.75 | AOC3 (0.42) | LMNAMIFTAAR1POLB | |
| SCHEMBL142722 | 0.75 | AOC3 (0.42) | LMNAMIFTAAR1POLB | |
| SCHEMBL27540029 | 0.74 | HRH1 (0.47) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL9490631 | 0.74 | TRPA1 (0.67) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL9467887 | 0.74 | MIF (0.49) | TRPA1LMNAFFAR1MEN1KMT2A | |
| SCHEMBL143657 | 0.72 | POLB (0.45) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |