Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345729 | 0.82 | DRD2 (0.43) | ALDH1A1MAOAMAPTHPGDKDM4E | |
| SCHEMBL14345736 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL14345925 | 0.77 | PDE5A (0.47) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL14345705 | 0.72 | BCHE (0.50) | ALDH1A1TSHRMAPTPDE5ACYP1A2 | |
| SCHEMBL14345846 | 0.71 | ALDH1A1 (0.48) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL14425146 | 0.70 | MAOA (0.46) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL8792194 | 0.69 | ALDH1A1 (0.62) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL4699059 | 0.67 | MAPT (0.41) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL17895740 | 0.66 | KDM4E (0.61) | ALDH1A1TSHRMAOAMAPTALOX15 | |
| SCHEMBL22118133 | 0.66 | KDM4E (0.66) | ALDH1A1TSHRMAOAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138081-A1 | PYRIMIDINO[1',6'-1,2]PYRIDO[3,4-b]INDOLE DERIVATIVES AND THEIR THERAPEUTIC USAGE | FOURTILLAN (FR) | 2007-12-06 | — | — | WO | disclosed |