Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345726 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMAPTMAOA | |
| SCHEMBL14345923 | 0.79 | KDM4E (0.44) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL4699104 | 0.76 | KDM4E (0.47) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL14345706 | 0.76 | CYP1A2 (0.53) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL4698526 | 0.72 | HSD17B10 (0.42) | DRD2DRD1DRD5DRD3KDM4E | |
| Methane SCHEMBL5632637 | 0.72 | KDM4E (0.43) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL4702160 | 0.70 | ALOX15 (0.41) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL8025896 | 0.70 | DRD2 (0.44) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL13219185 | 0.68 | HSD17B10 (0.46) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL7843326 | 0.68 | NOTUM (0.47) | DRD2DRD1DRD5DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138081-A1 | PYRIMIDINO[1',6'-1,2]PYRIDO[3,4-b]INDOLE DERIVATIVES AND THEIR THERAPEUTIC USAGE | FOURTILLAN (FR) | 2007-12-06 | — | — | WO | disclosed |