Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374655 | 0.82 | MTNR1A (0.32) | KDM4E | |
| SCHEMBL14347640 | 0.79 | KDM4E (0.43) | KDM4E | |
| SCHEMBL14347635 | 0.77 | NQO2 (0.32) | — | |
| SCHEMBL14347277 | 0.76 | KDM4E (0.56) | KDM4E | |
| SCHEMBL14347284 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL14347495 | 0.73 | MAOA (0.49) | KDM4E | |
| SCHEMBL14347313 | 0.71 | KDM4E (0.36) | KDM4E | |
| SCHEMBL14347543 | 0.70 | TNKS (0.39) | — | |
| SCHEMBL14347463 | 0.70 | PRKDC (0.39) | KDM4E | |
| SCHEMBL14347431 | 0.69 | NPC1 (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |