Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110289 | 0.84 | PPM1B (0.37) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL10137516 | 0.84 | MAPT (0.34) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL13110286 | 0.80 | GAA (0.33) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL13110285 | 0.78 | OGA (0.34) | MAPTALDH1A1GAACAPN9 | |
| SCHEMBL10841947 | 0.76 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12701406 | 0.75 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL15186887 | 0.73 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18072163 | 0.73 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL426312 | 0.70 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL13920579 | 0.70 | KMT2A (0.34) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130023644-A1 | BETA-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-01-24 | — | — | US | disclosed |
| US-7304165-B2 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-20070154882-A1 | Beta-polypeptides that inhibit cytomegalovirus infection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070123709-A1 | Beta-amino acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123709-A1 | Beta-amino acids | BCAT1, MARCKS, YWHAZ | MAPT 2911/4885ALDH1A1 4837/4885MEN1 1614/4885 |
| US-20130023644-A1 | BETA-AMINO ACIDS | BCAT1, MARCKS, YWHAZ | MAPT 2911/4885ALDH1A1 4837/4885MEN1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.