Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481090 | 0.85 | TSHR (0.68) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL8613867 | 0.84 | MAPT (0.82) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL11153486 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL11278251 | 0.81 | TSHR (1.00) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL9339546 | 0.81 | MEN1 (0.58) | ALDH1A1KDM4EMAPK1L3MBTL1MAPT | |
| SCHEMBL12577217 | 0.81 | MAPT (1.00) | ALDH1A1MAPK1L3MBTL1TSHRMAPT | |
| SCHEMBL12575381 | 0.81 | MAPT (1.00) | ALDH1A1MAPK1L3MBTL1TSHRMAPT | |
| Levodropropizine SCHEMBL29043 | 0.81 | ADRA2A (1.00) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| Dropropizine SCHEMBL8379428 | 0.81 | ADRA2A (1.00) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| Dropropizine SCHEMBL93975 | 0.81 | ADRA2A (1.00) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291624-B2 | CDK-inhibitory pyrimidines, their production and use as pharmaceutical agents | BAYER SCHERING PHARMA AG (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7235561-B2 | Compound and a composition including such a compound | SCHERING AG (DE) | 2007-06-26 | — | — | US | disclosed |
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| CN-1026248-C | Method and sensing electrode system for electrochemical determination of analytes and oxidoreductases | BOEHRINGER MANNHEIM GMBH | 1994-10-19 | — | — | CN | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| CN-1054666-A | Be used for the method for electrochemical determination of analyte or oxidoreducing enzyme and sensitive electrode system and for this reason and the compound that uses | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-18 | — | — | CN | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |