SCHEMBL143560

SCHEMBL143560

CC(CN)Cn1ccnc1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.46
CYP19A1 P11511 1/20 0.44
TBXAS1 P24557 2/20 0.42
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
QPCT Q16769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581654 0.82 FDPS (0.47) FDPSCYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL20953982 0.82 FDPS (0.47) FDPSCYP19A1TBXAS1CYP11B1CYP11B2
Iodide SCHEMBL4367921 0.80 FDPS (0.46) FDPSCYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL4681300 0.80 FDPS (0.50) FDPSTBXAS1
SCHEMBL4681306 0.80 FDPS (0.50) FDPSCYP19A1TBXAS1CYP11B1CYP11B2
SCHEMBL14738593 0.79
SCHEMBL1369052 0.79
SCHEMBL171211 0.79
SCHEMBL17484070 0.78 TBXAS1 (0.47) FDPSCYP19A1TBXAS1CYP11B1CYP11B2
Bromide SCHEMBL18191796 0.78 FDPS (0.47) FDPSCYP19A1TBXAS1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113046751-A Conductive metal vapor phase corrosion inhibitor and application thereof 浙江工业大学 2021-06-29 CN claimed
WO-2025215201-A1 PANNEXIN-1 INHIBITORS AND USES THEREOF PANNTHERAPI (FR) 2025-10-16 WO disclosed
CN-116217889-A High-strength and high-toughness self-repairing supermolecular polyurethane elastomer based on thiolactone chemistry and preparation method thereof 西北工业大学 2023-06-06 CN disclosed
CN-108456179-B Compound TVA-X with neuroprotective effect and preparation method and application thereof 雷鹏程 2021-09-28 CN disclosed
CN-113046751-A Conductive metal vapor phase corrosion inhibitor and application thereof 浙江工业大学 2021-06-29 CN disclosed
US-20150126679-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES HENKEL AG & CO KGAA (DE) 2015-05-07 US disclosed
US-20150126669-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES HENKEL AG & CO KGAA (DE) 2015-05-07 US disclosed
EP-2430073-B1 CATIONIC BENZOXAZINE (CO)POLYMERS HENKEL AG & CO KGAA (DE) 2015-01-07 EP disclosed
EP-2430137-B1 COLOR-PROTECTING WASHING OR CLEANING AGENT HENKEL AG & CO KGAA (DE) 2014-11-12 EP disclosed
US-8580726-B2 Color-protecting washing or cleaning agent HENKEL AG & CO. KGAA (DE) 2013-11-12 US disclosed
EP-0293500-A1 3-heteroalkyl-2,4.quinzaoline-diones AMERICAN CYANAMID COMPANY (US) 1988-12-07 EP disclosed
US-4753944-A INHIBITING THROMBOXANE SYNTHETASE AMERICAN CYANAMID COMPANY (US) 1988-06-28 US disclosed
US-4728663-A HYPOTENSIVE, ANTIARRHYTHMIA AMERICAN CYANAMID COMPANY (US) 1988-03-01 US disclosed
US-4710502-A THROMBOXANE SYNTHETASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1987-12-01 US disclosed
US-4684654-A THROMBOXANE SYNTHETASE INHIBITORS, HYPOTENSIVES AMERICAN CYANAMID COMPANY (US) 1987-08-04 US disclosed
EP-0230035-A2 Omega-[(hetero)alkyl]benz[cd]indol-2-amines AMERICAN CYANAMID COMPANY (US) 1987-07-29 EP disclosed
US-4680293-A 3-imidazolylalkyl-, triazolylalkyl-, pyridinylalkyl-1,2,3-benzotriazin-4(3H)-ones and derivatives thereof AMERICAN CYANAMID COMPANY (US) 1987-07-14 US disclosed
US-4568687-A THROMBOXANE SYNTHETASE TNZYME INHIBITORS; HYPOTENSIVE AGENTS, CARDIOTONIC AGENTS AMERICAN CYANAMID COMPANY (US) 1986-02-04 US disclosed
US-4555519-A Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)alkyl]pyridinecarboxamides AMERICAN CYANAMID COMPANY (US) 1985-11-26 US disclosed
EP-0117462-A2 N-(2-4-(1H-imidazol-1-yl)alkyl)arylamides AMERICAN CYANAMID COMPANY (US) 1984-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126679-A1 POLYMERIZABLE BENZOXAZINE COMPOUNDS WITH INTERFACIAL ACTIVE OR SURFACE ACTIVE PROPERTIES CYP4Z1, PRDX4, PRDX1 FDPS 1566/4885CYP19A1 291/4885TBXAS1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.