Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | MPL | P40238 | 8/20 | 0.58 |
| ▸ | CTRC | Q99895 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.57 |
| ▸ | PTPRB | P23467 | 1/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435931 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL107958 | 0.99 | CYP1A2 (0.63) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL107959 | 0.99 | CYP1A2 (0.63) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL3188963 | 0.98 | CYP1A2 (0.62) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL1435929 | 0.89 | CYP1A2 (0.54) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL24026914 | 0.84 | PRMT1 (0.50) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL24026725 | 0.83 | HPGD (0.51) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL8912216 | 0.83 | CYP1A2 (0.64) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL29259111 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL11854027 | 0.82 | HPGD (0.56) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| US-9173829-B2 | Compositions for dyeing keratin fibers | HENKEL AG & CO. KGAA (DE) | 2015-11-03 | — | — | US | disclosed |
| US-9161898-B2 | Compositions for colouring keratin fibres | HENKEL AG & CO. KGAA (DE) | 2015-10-20 | — | — | US | disclosed |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2014-10-09 | — | — | US | disclosed |
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | HENKEL AG & CO. KGAA (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-1844109-B1 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | PROCTER & GAMBLE (US) | 2011-03-30 | — | — | EP | disclosed |
| US-7658771-B2 | Coloring agents for keratin fibers | THE PROCTER & GABLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20100021396-A1 | TINTING MOUSSE | HENKEL AG & CO. KGAA (DE) | 2010-01-28 | — | — | US | disclosed |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | WELLA OPERATIONS US, LLC | 2009-06-25 | — | — | US | disclosed |
| US-7537620-B2 | Agent for coloring keratin fibers | WELLA AG (DE) | 2009-05-26 | — | — | US | disclosed |
| US-20070258928-A1 | Agent for Coloring Keratin Fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | disclosed |
| US-20070199161-A1 | Coloring agents for keratin fibers | WELLA OPERATIONS US, LLC | 2007-08-30 | — | — | US | disclosed |
| EP-1820537-A1 | Agents for coloring keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-22 | — | — | EP | disclosed |
| US-20070067925-A1 | Agent for simultaneously lightening and coloring of fibers | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| EP-1759685-A1 | Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
| US-20070022545-A1 | Use of cationic azacyanine dyes for coloring keratin fibers | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | disclosed |
| US-20070011821-A1 | Agents for coloring keratin fibers | WELLA OPERATIONS US, LLC | 2007-01-18 | — | — | US | disclosed |
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| US-6485529-B1 | Agent and method for coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | KRT18, DSG1, PKN1 | CYP1A2 1749/4885CYP2C9 1717/4885TSHR 4427/4885 |
| US-20070067925-A1 | Agent for simultaneously lightening and coloring of fibers | KIT, KRT18, H1-5 | CYP1A2 1696/4885CYP2C9 1797/4885TSHR 2254/4885 |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | KRT18, PKN3, IK | CYP1A2 3680/4885CYP2C9 4227/4885TSHR 2518/4885 |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | KRT18, TPM4, TUBB1 | CYP1A2 1062/4885CYP2C9 2073/4885TSHR 3917/4885 |
| US-20070022545-A1 | Use of cationic azacyanine dyes for coloring keratin fibers | KRT18, AZI2, MKI67 | CYP1A2 1505/4885CYP2C9 1504/4885TSHR 4326/4885 |
| US-20070258928-A1 | Agent for Coloring Keratin Fibers | KRT18, TUBB1, TUBA4A | CYP1A2 4278/4885CYP2C9 4728/4885TSHR 3629/4885 |
| US-20100021396-A1 | TINTING MOUSSE | KRT18, MSN, MFAP1 | CYP1A2 2191/4885CYP2C9 3411/4885TSHR 2779/4885 |
| US-20070011821-A1 | Agents for coloring keratin fibers | KRT18, IK, DSG1 | CYP1A2 3840/4885CYP2C9 4116/4885TSHR 4598/4885 |
| US-20070199161-A1 | Coloring agents for keratin fibers | KRT18, IK, KRTCAP2 | CYP1A2 3517/4885CYP2C9 3650/4885TSHR 4824/4885 |
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | KRT18, IK, NUP205 | CYP1A2 2322/4885CYP2C9 2484/4885TSHR 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.