SCHEMBL14360693

SCHEMBL14360693

O=C(NO)Nc1ccc2[nH]nnc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
ROCK2 O75116 4/20 0.40
ROCK1 Q13464 4/20 0.40
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
CD40 P25942 1/20 0.38
CD40LG P29965 1/20 0.38
MAPT P10636 4/20 0.38
TP53 P04637 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156215 0.83 PEPD (0.42) ROCK2ROCK1ALDH1A1CD40CD40LG
SCHEMBL1247686 0.83 ROCK2 (0.55) ROCK2ROCK1KDM4EALDH1A1HPGD
SCHEMBL9172845 0.81 ROCK2 (0.54) ROCK2ROCK1KDM4EALDH1A1HPGD
SCHEMBL14093907 0.80 KDM4E (0.44) ROCK2ROCK1KDM4EALDH1A1RAB9A
SCHEMBL13318845 0.80 CD40 (0.35) CD40CD40LG
SCHEMBL4447236 0.79 EGFR (0.46) KDM4EALDH1A1MAPTNPC1RAB9A
SCHEMBL26885093 0.79 ALDH1A1 (0.48) CA2CA9KDM4EALDH1A1HPGD
SCHEMBL3734462 0.79 SMN1; SMN2 (0.46) CA2CA9MAPTTP53NPC1
SCHEMBL10949559 0.79 MAP2K7 (0.45) LMNA
SCHEMBL6519579 0.79 TERT (0.48) CA2KDM4ECD40CD40LGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309564-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-18 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
EP-1431813-B1 Photothermographic material with high iodide content and image forming method using same FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
US-7157218-B2 Suppressed fogging and printout and is excellent in storage stability of an image against stain FUJIFILM CORPORATION (JP) 2007-01-02 US disclosed