SCHEMBL1247686

SCHEMBL1247686

CC(=O)Nc1ccc2[nH]nnc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.55
ROCK1 Q13464 1/20 0.55
KDM4E B2RXH2 7/20 0.54
KMT2A Q03164 4/20 0.54
MAPT P10636 4/20 0.54
MEN1 O00255 3/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
GLA P06280 1/20 0.54
TNNI3 P19429 1/20 0.54
TNNT2 P45379 1/20 0.54
TNNC1 P63316 1/20 0.54
RUNX1 Q01196 1/20 0.54
CBFB Q13951 1/20 0.54
PABPC1 P11940 1/20 0.51
MTNR1A P48039 2/20 0.48
MTNR1B P49286 2/20 0.48
ALDH1A1 P00352 4/20 0.47
PSMB8 P28062 2/20 0.47
HPGD P15428 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172845 0.98 ROCK2 (0.54) ROCK2ROCK1KDM4EKMT2AMAPT
SCHEMBL11307021 0.87 KDM4E (0.51) ROCK2ROCK1KDM4EKMT2AMAPT
SCHEMBL1248942 0.86 CD40 (0.53) ROCK2ROCK1KDM4EKMT2AMAPT
SCHEMBL8761617 0.85 BAZ1A (0.51) ROCK2ROCK1KDM4EKMT2AMAPT
SCHEMBL1156215 0.84 PEPD (0.42) ROCK2ROCK1KMT2AMAPTMEN1
SCHEMBL26885093 0.83 ALDH1A1 (0.48) KDM4EKMT2AMAPTMEN1NPC1
SCHEMBL14360693 0.83 CA2 (0.46) ROCK2ROCK1KDM4EKMT2AMAPT
SCHEMBL2704274 0.81 ALDH1A1 (0.50) KDM4EKMT2AMAPTMEN1NPC1
SCHEMBL10949559 0.80 MAP2K7 (0.45)
SCHEMBL3734462 0.80 SMN1; SMN2 (0.46) KMT2AMAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102037157-B Adhesion promotion of metal to laminate with a multi-functional compound ENTHONE 2014-05-28 CN claimed
CN-102037157-A Adhesion promotion of metal to laminate with a multi-functional compound ENTHONE 2011-04-27 CN claimed
CN-119702079-A Preparation method of composite material for cooperatively treating unsymmetrical dimethylhydrazine sewage by ozone photocatalysis 北方工业大学 2025-03-28 CN disclosed
US-8519074-B2 Comb polymers for supramolecular nanoconfinement The University of Massachusettes (US) 2013-08-27 US disclosed
US-20110178190-A1 COMB POLYMERS FOR SUPRAMOLECULAR NANOCONFINEMENT NATIONAL SCIENCE FOUNDATION 2011-07-21 US disclosed
US-7879893-B2 Zinc binding ligand; sustained release of insulin NOVO NORDISK A/S (DK) 2011-02-01 US disclosed
US-7879893-B2 Zinc binding ligand; sustained release of insulin NOVO NORDISK A/S (DK) 2011-02-01 US disclosed
US-7879893-B2 Zinc binding ligand; sustained release of insulin NOVO NORDISK A/S (DK) 2011-02-01 US disclosed
US-20090123563-A1 Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand NOVO NORDISK A/S (DK) 2009-05-14 US disclosed
US-20090123563-A1 Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand NOVO NORDISK A/S (DK) 2009-05-14 US disclosed
US-20090123563-A1 Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand NOVO NORDISK A/S (DK) 2009-05-14 US disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed
US-4820622-A RELEASING DIFFUSIBLE DYE IN ALKALINE SYSTEM AFTER HALIDE REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-04-11 US disclosed
US-4783396-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-11-08 US disclosed
US-4770990-A Silver halide photographic light-sensitive material containing a compound capable of imagewise releasing a photographically useful group during development FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4740453-A Silver halide photosensitive material containing a compound capable of releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
EP-0220746-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1987-05-06 EP disclosed
US-4649096-A EXPOSURE, DEVELOPMENT, ALKALI HYDROXIDE, ALKANOLAMINE, SULFITE, THIOSULFATE, P-DIHYDROXYBENZENE MITSUBISHI PAPER MILLS, LTD. (JP) 1987-03-10 US disclosed
US-4636456-A EXPOSURE, SILVER HALIDE EMULSIONS, HYDROQUINONE OR ESTER OR CARBONATE, DEVELOPMENT INHIBITORS FUJI PHOTO FILM CO., LTD. (JP) 1987-01-13 US disclosed
EP-0198438-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123563-A1 Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand IAPP, IRS1, HBB ROCK2 4807/4885ROCK1 4676/4885KDM4E 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.