SCHEMBL9172845

SCHEMBL9172845

CC(=O)Nc1ccc2[nH]nnc2c1.[Ag]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.54
ROCK1 Q13464 1/20 0.54
KDM4E B2RXH2 7/20 0.53
MAPT P10636 5/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
GLA P06280 1/20 0.53
TNNI3 P19429 1/20 0.53
TNNT2 P45379 1/20 0.53
TNNC1 P63316 1/20 0.53
RUNX1 Q01196 1/20 0.53
CBFB Q13951 1/20 0.53
PABPC1 P11940 1/20 0.50
MTNR1A P48039 2/20 0.47
MTNR1B P49286 2/20 0.47
ALDH1A1 P00352 4/20 0.46
PSMB8 P28062 2/20 0.46
HPGD P15428 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1247686 0.98 ROCK2 (0.55) ROCK2ROCK1KDM4EMAPTKMT2A
SCHEMBL11307021 0.86 KDM4E (0.51) ROCK2ROCK1KDM4EMAPTKMT2A
SCHEMBL1248942 0.84 CD40 (0.53) ROCK2ROCK1KDM4EMAPTKMT2A
SCHEMBL8761617 0.84 BAZ1A (0.51) ROCK2ROCK1KDM4EMAPTKMT2A
SCHEMBL1156215 0.83 PEPD (0.42) ROCK2ROCK1MAPTKMT2AMEN1
SCHEMBL26885093 0.82 ALDH1A1 (0.48) KDM4EMAPTKMT2AMEN1NPC1
SCHEMBL14360693 0.81 CA2 (0.46) ROCK2ROCK1KDM4EMAPTKMT2A
SCHEMBL2704274 0.80 ALDH1A1 (0.50) KDM4EMAPTKMT2AMEN1NPC1
SCHEMBL10949559 0.79 MAP2K7 (0.45)
SCHEMBL3734462 0.79 SMN1; SMN2 (0.46) MAPTKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144087-B2 Heat-developable color light-sensitive material KONISHIROKU PHOTO IND (JP) 1995-05-24 EP disclosed
EP-0174135-B2 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-06-17 EP disclosed
EP-0144087-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-18 EP disclosed
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
US-4840882-A CONTAINING A VINYL SULFONYL HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed
EP-0174135-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1989-04-26 EP disclosed
US-4770981-A MULTILAYER, DIFFUSION TRANSFER MATERIAL HAVING SPECIFIC BINDER CONCENTRATION; ANTIFOGGING AGENTS; COLOR SEPARATION; PHOTOTHERMOGRAPHY; DRY TREATMENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
EP-0174135-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1986-03-12 EP disclosed
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 EP disclosed
EP-0144087-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1985-06-12 EP disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed