Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | TPMT | P51580 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30486023 | 1.00 | TSHR (0.63) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL6409033 | 0.87 | CYP2C9 (0.66) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4183893 | 0.83 | KMT2A (0.65) | MAPTLMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14388233 | 0.81 | CYP2C9 (0.63) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17035531 | 0.81 | CYP2C9 (0.58) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL1436447 | 0.79 | TUBB4A (0.50) | TSHRCYP3A4TPMTMAPTLMNA | |
| SCHEMBL10566813 | 0.79 | CTSL (0.46) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10566336 | 0.79 | CTSL (0.46) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13216464 | 0.79 | HSP90AA1 (0.77) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17321082 | 0.78 | L3MBTL1 (0.64) | TSHRCYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181306-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | THE BOARD AND TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2023-06-15 | — | — | US | claimed |
| EP-3920846-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | The Board and Trustees of the Leland Stanford Junior University (US) | 2021-12-15 | — | — | EP | claimed |
| WO-2020163654-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | MCGRANE PAUL LEO (US) | 2020-08-13 | — | — | WO | claimed |
| US-20200246127-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | THE BOARD AND TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-08-06 | — | — | US | claimed |
| US-9603354-B2 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2017-03-28 | — | — | US | claimed |
| US-7977383-B2 | Containing alkali ions, electrolytes, a buffer, polyol, saccharide and hydroxamic acid derivatives | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2011-07-12 | — | — | US | claimed |
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | claimed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | claimed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | claimed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | claimed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | claimed |
| EP-4248959-A1 | PREPARATION FOR REDUCTION OF PATHOLOGICAL IRON OVERLOAD | Dr. Franz Köhler Chemie GmbH (DE) | 2023-09-27 | — | — | EP | disclosed |
| US-20230181306-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | THE BOARD AND TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
| EP-3920846-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | The Board and Trustees of the Leland Stanford Junior University (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020163654-A1 | BIOLOGICALLY MODIFIED VASCULAR GRAFTS FOR IMPROVED BYPASS SURGERY OUTCOMES | MCGRANE PAUL LEO (US) | 2020-08-13 | — | — | WO | disclosed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | disclosed |
| EP-1859679-A1 | Protective solution for preventing ischaemia damage | Dr. Franz Köhler Chemie GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | disclosed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215781-A1 | Protective solutions for organs | GLS, CA1, SI | TSHR 3653/4885CYP2C9 4484/4885CYP2C19 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.