Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282793 | 0.88 | HPGD (0.50) | MAPTHPGDALDH1A1 | |
| SCHEMBL3630523 | 0.84 | ALDH1A1 (0.59) | CES2CES1ALOX15TSHRCYP1A2 | |
| SCHEMBL25060930 | 0.81 | ALDH1A1 (0.48) | MAPTHPGDALDH1A1 | |
| SCHEMBL25212250 | 0.80 | CES2 (0.50) | CES2CES1ALOX15TSHRCYP1A2 | |
| SCHEMBL93592 | 0.79 | ALDH1A1 (0.54) | CES2CES1HPGDALDH1A1TDP1 | |
| SCHEMBL11004534 | 0.78 | CES2 (0.48) | CES2CES1ALOX15TSHRCYP1A2 | |
| SCHEMBL22259649 | 0.78 | HPGD (0.53) | CES2CES1ALOX15TSHRCYP1A2 | |
| SCHEMBL11210006 | 0.78 | CES2 (0.48) | CES2CES1ALOX15TSHRCYP1A2 | |
| SCHEMBL3300602 | 0.77 | ALDH1A1 (0.64) | ALOX15TSHRMAPTHPGDALDH1A1 | |
| SCHEMBL623946 | 0.77 | PKM (0.56) | CES2CES1ALOX15TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | claimed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | claimed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | claimed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | claimed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | claimed |
| US-9603354-B2 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-7977383-B2 | Containing alkali ions, electrolytes, a buffer, polyol, saccharide and hydroxamic acid derivatives | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-1859679-B1 | Protective solution for preventing ischaemia damage | KOEHLER CHEMIE DR FRANZ (DE) | 2009-10-28 | — | — | EP | disclosed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | disclosed |
| EP-1859679-A1 | Protective solution for preventing ischaemia damage | Dr. Franz Köhler Chemie GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | disclosed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0115156-A2 | Light sensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215781-A1 | Protective solutions for organs | GLS, CA1, SI | CES2 1601/4885CES1 1096/4885ALOX15 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.