Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.74 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363416 | 0.88 | P2RX1 (0.64) | P2RX1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL8406630 | 0.86 | P2RX1 (0.75) | P2RX1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL14363185 | 0.86 | FADS1 (0.67) | P2RX1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13189703 | 0.85 | P2RX1 (1.00) | P2RX1TMPRSS4FADS1SLC2A1P2RX4 | |
| SCHEMBL14394718 | 0.82 | P2RX1 (0.78) | P2RX1TMPRSS4KCNK3KCNK9RAB9A | |
| SCHEMBL16127835 | 0.81 | P2RX1 (0.64) | P2RX1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL5464222 | 0.81 | P2RX1 (0.67) | P2RX1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL14363191 | 0.80 | MAOB (0.60) | P2RX1TMPRSS4NPC1RAB9AALDH1A1 | |
| SCHEMBL14363287 | 0.80 | GPR17 (0.63) | P2RX1TMPRSS4KCNK3KCNK9NPC1 | |
| SCHEMBL14200567 | 0.80 | MEN1 (0.67) | KCNK3KCNK9NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | P2RX1 4478/4885TMPRSS4 342/4885KCNK3 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.