Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180854 | 0.78 | HSD17B10 (0.53) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL14846515 | 0.77 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL13074842 | 0.77 | ERCC1 (0.41) | ERCC1FEN1ERCC4KDM4EHSD17B10 | |
| SCHEMBL16622498 | 0.75 | DAO (0.41) | ERCC1FEN1ERCC4KDM4EHSD17B10 | |
| SCHEMBL5030756 | 0.74 | DAO (0.61) | ERCC1FEN1ERCC4KDM4EHSD17B10 | |
| SCHEMBL12414070 | 0.74 | HSD17B10 (0.45) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL12506518 | 0.74 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL14627848 | 0.74 | LMNA (0.47) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL4469971 | 0.74 | ALDH1A1 (0.51) | KDM4EHSD17B10ALDH1A1POLBKMT2A | |
| SCHEMBL28113666 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | claimed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | claimed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | claimed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | claimed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | claimed |
| US-9603354-B2 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-7977383-B2 | Containing alkali ions, electrolytes, a buffer, polyol, saccharide and hydroxamic acid derivatives | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-1859679-B1 | Protective solution for preventing ischaemia damage | KOEHLER CHEMIE DR FRANZ (DE) | 2009-10-28 | — | — | EP | disclosed |
| CN-100448440-C | Protective solution for preventing local ischemic damage | FRANTZ KOLER DR CHEMICAL GMBH (DE) | 2009-01-07 | — | — | CN | disclosed |
| EP-1859679-A1 | Protective solution for preventing ischaemia damage | Dr. Franz Köhler Chemie GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| CN-1480132-A | Protective solution for preventing local ischemic damage | �����ġ����ղ�ʿ��ѧ����˾ | 2004-03-10 | — | — | CN | disclosed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0030861-A2 | Isoquinoline acetic acids and pharmaceutical compositions thereof | PFIZER INC. (US) | 1981-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215781-A1 | Protective solutions for organs | GLS, CA1, SI | ERCC1 1660/4885FEN1 1248/4885ERCC4 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.