Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364159 | 0.84 | CHRNA7 (0.55) | CHRNA7ADRA1DADRA1AADRA1BSLC6A4 | |
| SCHEMBL14364171 | 0.81 | CHRNA7 (0.49) | CHRNA7ADRA1DADRA1AADRA1BSLC6A4 | |
| SCHEMBL14364155 | 0.79 | ADRA1D (0.50) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL14363780 | 0.78 | KIF11 (0.42) | HPGDHSD17B10KIF11 | |
| SCHEMBL14363773 | 0.75 | ABCG2 (0.52) | ADRA1AMEN1KMT2AABCB1ABCG2 | |
| SCHEMBL3867321 | 0.71 | CHRNA7 (0.58) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648536 | 0.71 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648535 | 0.71 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648518 | 0.71 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL14364158 | 0.70 | ADRA1A (0.62) | CHRNA7ADRA1DADRA1AADRA1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |