Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 7/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736549 | 0.91 | LPL (0.41) | FASNLPLLIPGALDH1A1MAPT | |
| SCHEMBL14366251 | 0.88 | LPL (0.37) | FASNLPLLIPGCA2CA1 | |
| SCHEMBL14366249 | 0.84 | FASN (0.46) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL16591212 | 0.82 | FASN (0.44) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10552694 | 0.82 | FASN (0.44) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10551160 | 0.82 | FASN (0.44) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10555297 | 0.81 | FASN (0.43) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10550846 | 0.81 | SLC6A3 (0.43) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10551733 | 0.81 | FASN (0.43) | FASNCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10550706 | 0.80 | TSHR (0.52) | FASNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291367-B2 | Liquid-crystalline compounds | MERCK PATENT GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7291367-B2 | Liquid-crystalline compounds | MERCK PATENT GMBH (DE) | 2007-11-06 | — | — | US | disclosed |