SCHEMBL1436662

SCHEMBL1436662

C=CC(NC(=O)OCc1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.66
KLK1 P06870 4/20 0.63
TP53 P04637 1/20 0.61
PLAU P00749 7/20 0.60
F2 P00734 6/20 0.60
PLAT P00750 6/20 0.60
PLG P00747 6/20 0.56
KLK8 O60259 5/20 0.56
KLK4 Q9Y5K2 5/20 0.56
F10 P00742 4/20 0.56
PRTN3 P24158 2/20 0.56
KLK2 P20151 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1436931 0.83 POLB (0.52) ELANEKLK1TP53PLAUF2
SCHEMBL5689257 0.82 ELANE (0.77) ELANEKLK1TP53PLAUF2
SCHEMBL7403534 0.81 F2 (0.86) ELANEKLK1TP53PLAUF2
SCHEMBL9970972 0.80 ELANE (1.00) ELANEKLK1TP53PLAUF2
SCHEMBL5881673 0.80 ELANE (0.70) ELANEKLK1TP53PLAUF2
SCHEMBL9971041 0.78 PLAU (0.75) ELANEKLK1TP53PLAUF2
SCHEMBL7405303 0.76 CTRB1 (0.55) ELANE
SCHEMBL17126245 0.76 KLK1 (0.83) ELANEKLK1TP53PLAUF2
SCHEMBL12942620 0.75 KYNU (0.55) ELANEKLK1TP53PLAUF2
SCHEMBL22118319 0.75 CTRB1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2295082-B1 Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence FDS PHARMA ASS (GB) 2013-09-18 EP disclosed
EP-1394261-B1 ANTIGENS FOR IMMUNISATION FDS PHARMA ASS (GB) 2011-03-30 EP disclosed
EP-2295082-A1 Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence FDS Pharma Ass. (GB) 2011-03-16 EP disclosed
US-7560529-B2 Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence FDS Pharma (GB) 2009-07-14 US disclosed
WO-2008078177-A2 METHOD FOR PRODUCING CATALYTIC ANTIBODIES (VARIANTS), ANTIGENS FOR IMMUNIZATION AND NUCLEOTIDE SEQUENCE FDS PHARMA ASS. (RU) 2008-07-03 WO disclosed
US-20070178109-A1 Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence LIFEBIO LABORATORIES LLC 2007-08-02 US disclosed
US-20040265975-A1 glycoprotein 120; fusion proteins; myelin basic protein; autoimmune diseases; genetic vaccines FDS PHARMA ASS. (GB) 2004-12-30 US disclosed
EP-1394261-A2 METHOD FOR PRODUCING CATALYTIC ANTIBODIES (VARIANTS), ANTIGENS FOR IMMUNISATION AND NUCLEOTIDE SEQUENCE ASGL - Farmatsevticjeskie Innovatsii, Zaptryote Aktsionernoe Obschestvo (RU) 2004-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070178109-A1 Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence SSB, DNMT3L, NASP ELANE 1518/4885KLK1 812/4885TP53 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.