Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HMGCR | P04035 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374020 | 0.76 | KIF11 (0.40) | HSD17B10ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8147119 | 0.75 | MAPT (0.64) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL14374013 | 0.75 | FASN (0.41) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL8147865 | 0.74 | MAPT (0.62) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL11800701 | 0.73 | HSD17B10 (0.59) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL8144828 | 0.71 | HSD17B10 (0.66) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL9126180 | 0.71 | HMGCR (0.50) | HSD17B10ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14347051 | 0.70 | ALOX5 (0.61) | CYP3A4CYP2C9CYP2C19CYP1A2KMT2A | |
| SCHEMBL8145291 | 0.70 | HSD17B10 (0.51) | HSD17B10ALDH1A1MAPTHPGDTP53 | |
| SCHEMBL69624 | 0.70 | MAOB (0.59) | HSD17B10ALDH1A1MAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | NQO1, SDHA, SDHB | HSD17B10 470/4885ALDH1A1 122/4885MAPT 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.