Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TPI1 | P60174 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257058 | 0.82 | MVD (0.46) | MVDALDH1A1TPI1LPAR3LPAR2 | |
| SCHEMBL12234244 | 0.81 | MVD (0.45) | MVDMAPTTPI1LPAR3LPAR2 | |
| SCHEMBL10044364 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAKMT2ATP53 | |
| SCHEMBL12257897 | 0.73 | MVD (0.47) | MVDALDH1A1MAPTLPAR3LPAR2 | |
| SCHEMBL18963373 | 0.73 | CES2 (0.39) | ALDH1A1MAPTLMNAKMT2ATP53 | |
| SCHEMBL15945376 | 0.72 | KMT2A (0.48) | ALDH1A1MAPTLMNAKMT2ATP53 | |
| SCHEMBL12234243 | 0.71 | MVD (0.46) | MVDLPAR3LPAR2LPAR1 | |
| SCHEMBL18540716 | 0.71 | — | — | |
| SCHEMBL14878232 | 0.71 | TPI1 (0.64) | ALDH1A1MAPTTPI1LPAR3LPAR2 | |
| SCHEMBL14004129 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147252-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2007-12-27 | — | — | WO | disclosed |