Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079875 | 0.85 | — | — | |
| SCHEMBL12301654 | 0.81 | FPR2 (0.35) | CTSSCTSKKDM4EALDH1A1NPSR1 | |
| SCHEMBL14347466 | 0.80 | CTSS (0.38) | LMNACTSSCTSKMAPK1RNPEP | |
| SCHEMBL23065777 | 0.80 | CTSS (0.38) | LMNACTSSCTSKMAPK1RNPEP | |
| SCHEMBL26854829 | 0.80 | FOLH1 (0.34) | LMNACTSSCTSKRNPEPL3MBTL1 | |
| SCHEMBL14404929 | 0.79 | LMNA (0.51) | LMNAMAPK1RNPEPGAAL3MBTL1 | |
| SCHEMBL3869335 | 0.79 | LMNA (0.51) | LMNAMAPK1RNPEPGAAL3MBTL1 | |
| SCHEMBL23585048 | 0.79 | LMNA (0.41) | LMNAMAPK1RNPEPGAAL3MBTL1 | |
| SCHEMBL3869337 | 0.79 | LMNA (0.51) | LMNAMAPK1RNPEPGAAL3MBTL1 | |
| SCHEMBL20078588 | 0.79 | CTSS (0.40) | LMNACTSSCTSKMAPK1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |